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"I don't know what dietary advice he was given, but with Lomu heading towards dialysis, he should have been given advice not to take it," he said.
"There is no evidence that creatine hampers kidney function in a healthy patient. However, it could accelerate the loss of nephrons - the units that filter blood - in someone with a pre-existing condition.
"Excess creatine use can definitely exacerbate pre-existing kidney conditions."
Kalra said there is evidence that "massive people are more predisposed to nephrotic syndrome" and research has shown that Polynesians have a higher predisposition towards the condition than average.
Fitzpatrick, who captained Lomu and Vidiri for both the Blues and All Blacks, admits members of his Auckland side routinely took creatine, but insists its use was closely regulated.
"We had sports science and trainers at the time," he said. "It's all about the way you use creatine. It wasn't simply a case of being given a container and getting told: 'Go take it.'
"There was supervision, there was advice, and not everyone was on it. I certainly wasn't a big user of it myself."
Creatine has been a popular dietary supplement for rugby players for more than 20 years.
Former England scrum-half Kyran Bracken says players used it both in the run-up to, and during, the World Cup-winning campaign in 2003.
"Some of the players who wanted to get bigger certainly used creatine," Bracken told Telegraph Sport.
"I have no idea whether it's good or not to be honest. For me, it was more important to be light and fast and I didn't want to build up too much muscle, so I didn't use it. But a lot of the lads did, definitely."
Nutritionist Fred Wadsworth, who worked with England under Sir Clive Woodward, said any professional player who fails to use creatine is "missing a trick".
"Any forward would be mad not to take it because of the benefits in terms of bulk and power," he said.
"It is legal and has been widely used in rugby for two decades, without any problems. If you have underlying renal issues then it's not a good idea to take it though."